5 Types of People Who Should Avoid Eating Pomegranates

That burst of sweet tangy flavour from pomegranate seeds may feel like nature’s candy, and the fruit is widely praised for its antioxidants, vitamins, and heart boosting benefits. But health experts caution that not everyone should include pomegranates in their diet  for some, they could do more harm than good.
Certain individuals, such as those with allergies, digestive sensitivities, or on specific medications, may face unwanted side effects from the fruit. Studies published in European PMC and Research Gate indicate that while pomegranates offer many health benefits, they can also interfere with blood pressure, digestion, and drug metabolism in sensitive individuals.
1. People with Low Blood Pressure
Pomegranates help reduce high blood pressure thanks to their potassium and antioxidant content. However, for individuals already suffering from hypotension, this effect can be risky. Excessive consumption may cause dizziness, fainting, or blurred vision.
A meta analysis in European PMC found that drinking 300 mL of pomegranate juice daily lowered systolic blood pressure by 5 mmHg and diastolic by nearly 3 mmHg within two months beneficial for hypertensive patients but potentially harmful for those with already low readings.
2. People on Certain Medications
Pomegranate juice can interfere with how the liver processes several medications, including ACE inhibitors, statins, beta-blockers, and blood thinners. Research in Research Gate revealed that compounds in the fruit inhibit key liver enzymes (CYP3A4 and CYP2C9), causing drugs to remain in the system longer and increasing the risk of side effects.
Doctors also advise avoiding pomegranates for at least two weeks before surgery, as the fruit can influence blood clotting and react with anaesthesia.
3. People with Digestive Issues
Despite its high fibre content, pomegranate can cause bloating or cramping in people with sensitive digestion or irritable bowel syndrome (IBS). The fruit’s tannins may irritate the gut lining, while its hard seeds can strain digestion when consumed in excess.
4. People Allergic to Pomegranate
Though rare, pomegranate allergies can trigger serious symptoms such as rashes, throat swelling, itching, or even anaphylaxis. Individuals allergic to other fruits like peaches or apples may be more prone to similar reactions. Any sign of discomfort or burning sensations after eating pomegranate should be taken seriously, and medical advice should be sought immediately.
5. People Undergoing Surgery
Pomegranate compounds may affect how the body metabolises anaesthetic drugs and clotting mechanisms. Consuming the fruit before surgery can raise the risk of excessive bleeding or complications, which is why doctors recommend discontinuing it well ahead of any medical procedure.
Pomegranates remain one of the most nutrient dense fruits available, promoting heart health and immunity when consumed moderately. However, individuals with low blood pressure, those taking prescription medicines, patients with digestive issues, allergy sufferers, and anyone preparing for surgery should exercise caution or avoid the fruit altogether.
Disclaimer: This article is intended for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider before making dietary or lifestyle changes.